Daño del ADN en trabajadoras bananeras expuestas a plaguicidas en Limón, Costa Rica

 

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون: Ramírez, Vanessa, Cuenca, Patricia
التنسيق: artículo original
الحالة:Versión publicada
تاريخ النشر:2002
الوصف:Pesticide use in Costa Rica is very high and all year round. A high percentage of what is sprayed remains in the environment and in the living organisms around. This situation brings contamination and health problems to people in contact with them. The onset of adverse effects may be in the short or the long term, and symptoms vary widely, from headaches to cancer. Much research in this area has been devoted to acute or chronic effects, and not until recently to the genotoxic effect of pesticides. This study evaluated the genotoxic effect of pesticides used in banana packing activities, using the comet assay (single cell electrophoresis) as the biological marker in lymphocytes. This was a case-control double blind study of 30 exposed women from 15 banana farms and 28 women not occupationally exposed to pesticides from the same geographic area. Results show damage to single stranded DNA after working from 5 to 15 years (R2=0.12). In Costa Rica we do not have an historical record of the kind of pesticides used in banana farms, the period of time and for how long were they used. This prevented further analysis concerning dose, frequency of exposure and use of new or old kind of pesticides in the farms in relation to DNA damage. The comet assay is of value in the genetic monitoring of pesticide exposed populations.
البلد:Portal de Revistas UCR
المؤسسة:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
اللغة:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/16436
الوصول للمادة أونلاين:https://revistas.ucr.ac.cr/index.php/rbt/article/view/16436
Access Level:acceso abierto
كلمة مفتاحية:single cell electrophoresis
pesticides
human populations
lymphocytes
biomonitoring
Costa Rica
banana plantations
female farmers
DNA