Estudios citogenéticos en niños con Leucemia Linfocitica Aguda-B en Costa Rica

 

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書誌詳細
著者: Venegas, Patricia, Rivera, Julio
フォーマット: artículo original
状態:Versión publicada
出版日付:2004
その他の書誌記述:Cytogenetic studies in children with Acute Lymphocytic Leukemia-B in Costa Rica. Chromosome analyses were performed on bone marrow of 177 pediatric patients with Acute Lymphocytic Leukemia at the “Hospital Nacional de Niños”. The standard cytogenetic techniques now belongs to the panel of mandatory analyses performed at diagnosis of our acute leukemia patients and represent a major advantage to be effective and independent prognostic factors, essential for therapeutic choices. Cytogenetic results were achieved in 83% of the bone marrow samples: normal karyotypes represented 29% and abnormal karyotypes 71% with the follow distribution: t(9;22) 3%; t(1;19) 5%; t(4;11) 3%, Hyperdiploidy 39%; other chromosomal abnormalities 21%. Systematic cytogenetic analyses are essential to define morpho-immunologic sub-types of leukemia and to detect new translocations that allows to understand hematopoiesis and leukemogenesis. Rev. Biol. Trop. 52(3): 551-558. Epub 2004 Dic 15
国:Portal de Revistas UCR
機関:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
言語:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/33043
オンライン・アクセス:https://revistas.ucr.ac.cr/index.php/rbt/article/view/33043
Access Level:acceso abierto
キーワード:Acute Lymphocytic leukemia
cytogenetics
chromosomal abnormalities
prognostic factors
Costa Rica.