Diferencias en el Control Metabólico entre Adolescentes y Adultos con Diabetes Mellitus Tipo 1 en el Hospital San Juan De Dios, de Marzo a Agosto 2007
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| Formato: | artículo original |
| Estado: | Versión publicada |
| Fecha de Publicación: | 2012 |
| Descripción: | Background: Debut and/or progression of type 1 diabetes mellitus often occurs during adoles- cence, a stage characterized by the desire for independence and sometimes risky behaviors. The aim of the study was to compare glycemic control and epidemiology in adolescents and adults with type 1-Diabetes. Methods: We per- formed an observational cross-sectional study with 99 type 1 diabetics, assessing variables of medical history, laboratory results (glycemic control, urinary albumin excretion, lipid profile) and chronic micro and macrovascular complica- tions. Adolescents were defined as subjects aged 18 years or less and adults, subjects over 18. We performed a comparative analysis of the varia- bles between the adolescent group (n=34) and adult group (n=65) of the study. Results: The average age of the subjects was 25.0 ± 9.9 years, with an average duration of diabetes of 12.8 ± 8.6 years. There were statistically significant differences between adolescents and adults with type 1 diabetes in the following variables: age at diagnosis (P=0.005), baseline age (P=0.002), body mass index (P<0.001), presence of dyslipidemia (P<0.001), diabetic retinopathy (P=0.018) and diabetic nephropathy (P=0.001), insulin requirements (P=0.041), use of ACE inhibitors (P=0.001) and statins (P<0.001), HbA1c levels (P=0.009) and triglycerides (P=0.038). The average glycemic control was significantly worse in the adolescent group (HbA1c = 9.35 ± 2.26%) compared with adults (HbA1c = 8.23 ± 1.81%), however, this did not translate into increased prevalence of chronic complications at the time when analysis was made. Conclusions: Adolescence can exert a significant and deleterious effect on the metabol- ic control of type 1 diabetes mellitus compared with the adult stage of life. |
| País: | Portal de Revistas UCR |
| Institución: | Universidad de Costa Rica |
| Repositorio: | Portal de Revistas UCR |
| Lenguaje: | Español |
| OAI Identifier: | oai:portal.ucr.ac.cr:article/10434 |
| Acceso en línea: | https://revistas.ucr.ac.cr/index.php/clinica/article/view/10434 |
| Access Level: | acceso abierto |
| Palabra clave: | diabetes mellitus tipo 1 adolescencia macrovascular microvascular type 1 diabetes mellitus adolescence |