In vitro multiplication of Toxoplasma gondii and Trypanosoma cruzi in mouse, rat, and hamster astrocytes

 

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Detalles Bibliográficos
Autores: Troyo, Adriana, Chinchilla, Misael
Formato: artículo original
Estado:Versión publicada
Fecha de Publicación:2003
Descripción:The infection and multiplication of Toxoplasma gondii and Trypanosoma cruzi were compared in primary cultures of white rat, mouse and hamster astrocytes. These cells were cultured on cover slides and infected with T. gondii tachyzoites or T. cruzi blood trypomastigotes. Results show that hamster astrocytes are more susceptible to the multiplication of both parasites than rat and mouse cells. There was no statistical difference between the T. gondii infection in rat and mouse astrocytes (p<0.05), and this suggests an important role of other mechanisms or cells in the white rat natural resistance to this parasite. Because the hamster astrocytes are less resistant to these parasites multiplication and not necessarily to the invasion, any difference observed could be due to an intracellular effect: hamster brain astrocytes favor survival and multiplication of these parasites.
País:Portal de Revistas UCR
Institución:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Lenguaje:Inglés
OAI Identifier:oai:portal.ucr.ac.cr:article/15833
Acceso en línea:https://revistas.ucr.ac.cr/index.php/rbt/article/view/15833
Access Level:acceso abierto
Palabra clave:Toxoplasma gondii
Trypanosoma cruzi
cell culture
astrocyte
rat
mouse
hamster