Interference of lupus inhibitors in prothrombin time assays: effect of reagent variability. a case report.

 

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Autor: Quirós Quirós, William
Formato: artículo original
Estado:Versión publicada
Fecha de Publicación:2017
Descripción:Abstract: Lupus anticoagulant exerts an inhibitory effect on phospholipid-dependent coagulation tests, especially on TTP but also on PT. Depending on the type of reagents, its concentration, the technique of measurement and the heterogeneity of the antibodies, we can obtain discrepancies in the interpretation of the inhibitor. We present the case of a hemato-oncologic patient who developed a lupus inhibitor with the discrepancies in coagulation times that affected the clinical management of the patient.
País:Portal de Revistas UCR
Institución:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Lenguaje:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/30491
Acceso en línea:https://revistas.ucr.ac.cr/index.php/medica/article/view/30491
Access Level:acceso abierto
Palabra clave:anticoagulante lúpico
inhibidores de coagulación
antifosfolípidos
tiempo de protrombina
lupus anticoagulant
antiphospholipids
coagulation inhibitors
prothrombin time