Brucella melitensis: a nasty bug with hidden credentials for virulence

 

Enregistré dans:
Détails bibliographiques
Auteurs: Moreno, Edgardo, Moriyón, Ignacio
Format: artículo
Date de publication:2002
Description:On September 23, 1905, a cargo carrying 60 goats from Malta arrived in New York. The herd was kept in quarantine because of several deaths that occurred during the journey. Crewmen, an agent from the U.S. Bureau of Animal Industry, which was responsible for the shipment, and a woman who drank milk that “escaped” from the quarantine station displayed the characteristic symptoms of “Mediterranean fever.” Lieutenant Colonel David Bruce, a physician of the Royal Army, who discovered “Micrococcus melitensis ” in 1887 in infected British soldiers residing in Malta, had forewarned the U.S. sanitary authorities about the risk of “Mediterranean fever” by importing goats from Malta. In November 1906, after isolation of “M. melitensis,” the goats were destroyed. Almost 100 years after this episode, the genome sequence of Brucella melitensis (renamed after David Bruce) has been resolved by DelVecchio et al. (1), bringing new light to the understanding of the biology of this pathogen. The disease, known as brucellosis, is found in all continents, affecting mainly low-income countries; in addition, it constitutes a contemporary concern because Brucella strains are potential agents of biological warfare.
Pays:Repositorio UNA
Institution:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Langue:Inglés
OAI Identifier:oai:https://repositorio.una.ac.cr:11056/24293
Accès en ligne:http://hdl.handle.net/11056/24293
Access Level:acceso abierto
Mots-clés:BRUCELOSIS
MICROORGANISMOS
BACTERIAS
BRUCELLA
MICROORGANISMS
CAPRINOS