Intracellular adaptation of Brucella abortus

 

Enregistré dans:
Détails bibliographiques
Auteurs: Lamontagne, Julie, Forest, Anik, Marazzo, Elena, François, Denis, Butler, Heather, Michaud, Jean-François, Boucher, Lyne, Pedro, Ida, Villeneuve, Annie, Sitnikov, Dmitri, Trudel, Sylvie, Nassif, Najib, Boudjelt, Djamila, Tomaki, Fadi, Chaves-Olarte, Esteban, Guzman-Verri, Caterina, Brunet, Sylvain, Côté-Martin, Alexandra, Hunter, Joanna, Moreno, Edgardo, Paramithiotis, Eustache
Format: artículo
Date de publication:2009
Description:Macrophages were infected with virulent B. abortus strain 2308 or attenuated strain 19. Intracellular bacteria were recovered at different times after infection and their proteomes compared. The virulent strain initially reduced most biosynthesis and altered its respiration, adaptations reversed later in infection. The attenuated strain was unable to match the magnitude of the virulent strain’s adjustments. The results provide insight into mechanisms utilized by Brucella to establish intracellular infections
Pays:Repositorio UNA
Institution:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Langue:Inglés
OAI Identifier:oai:https://repositorio.una.ac.cr:11056/18373
Accès en ligne:http://hdl.handle.net/11056/18373
Access Level:acceso abierto
Mots-clés:BRUCELOSIS
BRUCELLA
BRUCELLA ABORTUS
VIRULENCE
ENFERMEDADES INFECCIOSAS
INTRACELLULAR INFECTION
BACTERIAS

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