Intracellular adaptation of Brucella abortus

 

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Dettagli Bibliografici
Autori: Lamontagne, Julie, Forest, Anik, Marazzo, Elena, François, Denis, Butler, Heather, Michaud, Jean-François, Boucher, Lyne, Pedro, Ida, Villeneuve, Annie, Sitnikov, Dmitri, Trudel, Sylvie, Nassif, Najib, Boudjelt, Djamila, Tomaki, Fadi, Chaves-Olarte, Esteban, Guzman-Verri, Caterina, Brunet, Sylvain, Côté-Martin, Alexandra, Hunter, Joanna, Moreno, Edgardo, Paramithiotis, Eustache
Natura: artículo
Data di pubblicazione:2009
Descrizione:Macrophages were infected with virulent B. abortus strain 2308 or attenuated strain 19. Intracellular bacteria were recovered at different times after infection and their proteomes compared. The virulent strain initially reduced most biosynthesis and altered its respiration, adaptations reversed later in infection. The attenuated strain was unable to match the magnitude of the virulent strain’s adjustments. The results provide insight into mechanisms utilized by Brucella to establish intracellular infections
Stato:Repositorio UNA
Istituzione:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Lingua:Inglés
OAI Identifier:oai:https://repositorio.una.ac.cr:11056/18373
Accesso online:http://hdl.handle.net/11056/18373
Access Level:acceso abierto
Keyword:BRUCELOSIS
BRUCELLA
BRUCELLA ABORTUS
VIRULENCE
ENFERMEDADES INFECCIOSAS
INTRACELLULAR INFECTION
BACTERIAS

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