Intracellular adaptation of Brucella abortus

 

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Detalhes bibliográficos
Autores: Lamontagne, Julie, Forest, Anik, Marazzo, Elena, François, Denis, Butler, Heather, Michaud, Jean-François, Boucher, Lyne, Pedro, Ida, Villeneuve, Annie, Sitnikov, Dmitri, Trudel, Sylvie, Nassif, Najib, Boudjelt, Djamila, Tomaki, Fadi, Chaves-Olarte, Esteban, Guzman-Verri, Caterina, Brunet, Sylvain, Côté-Martin, Alexandra, Hunter, Joanna, Moreno, Edgardo, Paramithiotis, Eustache
Formato: artículo
Fecha de Publicación:2009
Descrição:Macrophages were infected with virulent B. abortus strain 2308 or attenuated strain 19. Intracellular bacteria were recovered at different times after infection and their proteomes compared. The virulent strain initially reduced most biosynthesis and altered its respiration, adaptations reversed later in infection. The attenuated strain was unable to match the magnitude of the virulent strain’s adjustments. The results provide insight into mechanisms utilized by Brucella to establish intracellular infections
País:Repositorio UNA
Recursos:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Idioma:Inglés
OAI Identifier:oai:https://repositorio.una.ac.cr:11056/18373
Acesso em linha:http://hdl.handle.net/11056/18373
Access Level:acceso abierto
Palavra-chave:BRUCELOSIS
BRUCELLA
BRUCELLA ABORTUS
VIRULENCE
ENFERMEDADES INFECCIOSAS
INTRACELLULAR INFECTION
BACTERIAS