Optimization of a metabolic pathway in Escherichia coli for the production of farnesene through the use of synthetic biology
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| Autores: | , , , |
|---|---|
| Formato: | artículo original |
| Estado: | Versión publicada |
| Fecha de Publicación: | 2018 |
| Descripción: | Interest compounds generation using organic waste as raw material results in an economically and industrially viable option. Through synthetic biology is possible the design of microorganisms capable of using these residues as carbon sources in order to produce biofuels, vaccines, alcohol, oils and other products. Farnesene production and its precursors is possible through the genetic modification of microorganisms like Escherichia coli, introducing metabolic pathways capable of produce the interest compounds. After studying, optimizing and synthesizing the genes that make up the metabolic pathway of mevalonate, which originates farnesene, these were assembled together with several Anderson family promoters to transform E. coli and generate E, E, -farnesene from synthetic form. |
| País: | RepositorioTEC |
| Institución: | Instituto Tecnológico de Costa Rica |
| Repositorio: | RepositorioTEC |
| Lenguaje: | Español |
| OAI Identifier: | oai:repositoriotec.tec.ac.cr:2238/11823 |
| Acceso en línea: | https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/3957 https://hdl.handle.net/2238/11823 |
| Access Level: | acceso abierto |
| Palabra clave: | Biología sintética farneseno RFC10 ruta de mevalonato terpenoides Sinthetic biology farnesene mevalonate pathway terpenes |