Feasibility of dose enhancement assessment: preliminary results by means of Gd-infused polymer gel dosimeter and Monte Carlo study
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| Autores: | , , , , |
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| Formato: | artículo |
| Fecha de Publicación: | 2018 |
| Descripción: | This work reports the experimental development of an integral Gd-infused dosimeter suitable for Gd dose enhancement assessment along with Monte Carlo simulations applied to determine the dose enhancement by radioactive and X-ray sources of interest in conventional and electronic brachytherapy. In this context, capability to elaborate a stable and reliable Gd-infused dosimeter was the first goal aimed at direct and accurate measurements of dose enhancement due to Gd presence. Dose-response was characterized for standard and Gd-infused PAGAT polymer gel dosimeters by means of optical transmission/absorbance. The developed Gd-infused PAGAT dosimeters demonstrated to be stable presenting similar dose-response as standard PAGAT within a linear trend up to 13 Gy along with good post-irradiation readout stability verified at 24 and 48 hours. Additionally, dose enhancement was evaluated for Gd-infused PAGAT dosimeters by means of Monte Carlo (PENELOPE) simulations considering scenarios for isotopic and X-ray generator sources. The obtained results demonstrated the feasibility of obtaining a maximum enhancement around of (14±1)% for 192Ir source and an average enhancement of (70±13)% for 241Am. However, dose enhancement up to (267±18)% may be achieved if suitable filtering is added to the 241Am source. On the other hand, optimized X-ray spectra may attain dose enhancements up to (253±22) %, which constitutes a promising future alternative for replacing radioactive sources by implementing electronic brachytherapy achieving high dose levels. |
| País: | Repositorio UNA |
| Institución: | Universidad Nacional de Costa Rica |
| Repositorio: | Repositorio UNA |
| Lenguaje: | Inglés |
| OAI Identifier: | oai:https://repositorio.una.ac.cr:11056/23401 |
| Acceso en línea: | http://hdl.handle.net/11056/23401 |
| Access Level: | acceso abierto |
| Palabra clave: | POLYMERS POLIMEROS GD DOSE ENHANCEMENT PAGAT GEL DOSIMETRY RADIOTERAPIA ELECTRONIC BRACHYTHERAPY SIMULACIÓN POR COMPUTADOR RAYOS X RADIOISOTOPOS |