Colorectal cancer: Generalities, diagnosis, and biological therapies as new treatment options

 

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Bibliografische gegevens
Auteurs: Álvarez Vargas, Michelle, Herrera Aguilar, María José, Murillo Ugalde, Daniel, Quesada Lobo, Priscilla, Salazar Castro, Juan Diego, Mora Román, Juan José
Formaat: artículo de revisión
Publicatiedatum:2022
Omschrijving:The development of a malignant adenocarcinoma in the colon's inner layer or rectum wall is known as colorectal cancer. It is attributed to genetic information but also can be acquired due to lifestyle or environmental risk factors. The pathology is usually diagnosed through a colonoscopy. One promising alternative for its treatment is biological therapies. They are designed to improve, focus, or restore immune system function. These can be used to complement traditional treatment (e.g., surgery, radiotherapy, and chemotherapy). Immunotherapy is a classification of biological therapy, and it stimulates the immune system by generating a more effective therapeutic response in cancer treatment. It is possible to identify monoclonal antibodies, vaccines, oncological viruses, and novel methods such as chemoimmunotherapy, in which a cytotoxic agent and an immune response modifier are combined in a single drug. These options have brought promising results through several preclinical and clinical investigations.
Land:Kérwá
Instelling:Universidad de Costa Rica
Repositorio:Kérwá
Taal:Inglés
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/91653
Online toegang:https://storage.googleapis.com/journal-uploads/wjpps/article_issue/1664520801.pdf
https://hdl.handle.net/10669/91653
Keyword:colorectal cancer
biological therapies
monoclonal antibodies
vaccines
oncologic viruses
chemoinmunotherapy