Facilitation of ejaculation induced by 8-OH-DPAT does not produce conditioned place preference in male rats

 

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書誌詳細
著者: Camacho Barrios, Francisco Javier, Castro Rojas, María Dolores, Hernández, Valeria, Paredes Guerrero, Raúl Gerardo
フォーマット: artículo original
出版日付:2007
その他の書誌記述:The serotonin 1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) produces a drastic facilitation of ejaculation characterized by a significant reduction in the number of pre-ejaculatory intromissions and a shortening of ejaculation latency. In the present study, the authors evaluated whether this facilitation of ejaculation can induce a reward state assessed by conditioned place preference. Males treated with 0.1 or 1.0 mg/kg of 8-OH-DPAT showed a clear facilitation of ejaculation but did not develop conditioned place preference. These results clearly indicate that the pharmacological facilitation of ejaculation and the reduction of the number of intromissions does not necessarily make sex rewarding.
国:Kérwá
機関:Universidad de Costa Rica
Repositorio:Kérwá
言語:Inglés
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/85952
オンライン・アクセス:https://doi.apa.org/doiLanding?doi=10.1037%2F0735-7044.121.3.579
https://hdl.handle.net/10669/85952
キーワード:8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)
Conditioned Place Preference (CPP)
Sexual behavior
Reward