Facilitation of ejaculation induced by 8-OH-DPAT does not produce conditioned place preference in male rats

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書目詳細資料
Autores:	Camacho Barrios, Francisco Javier, Castro Rojas, María Dolores, Hernández, Valeria, Paredes Guerrero, Raúl Gerardo
格式:	artículo original
Fecha de Publicación:	2007
實物特徵:	The serotonin 1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) produces a drastic facilitation of ejaculation characterized by a significant reduction in the number of pre-ejaculatory intromissions and a shortening of ejaculation latency. In the present study, the authors evaluated whether this facilitation of ejaculation can induce a reward state assessed by conditioned place preference. Males treated with 0.1 or 1.0 mg/kg of 8-OH-DPAT showed a clear facilitation of ejaculation but did not develop conditioned place preference. These results clearly indicate that the pharmacological facilitation of ejaculation and the reduction of the number of intromissions does not necessarily make sex rewarding.
País:	Kérwá
機構:	Universidad de Costa Rica
Repositorio:	Kérwá
語言:	Inglés
OAI Identifier:	oai:kerwa.ucr.ac.cr:10669/85952
在線閱讀:	https://doi.apa.org/doiLanding?doi=10.1037%2F0735-7044.121.3.579 https://hdl.handle.net/10669/85952
Palabra clave:	8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) Conditioned Place Preference (CPP) Sexual behavior Reward