507. Association of NRXN3 deletion with schizophrenia and bipolar disorder
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| Autoři: | , , , , , , , , , , , , , , |
|---|---|
| Médium: | actas de congreso |
| Datum vydání: | 2017 |
| Popis: | Schizophrenia (SZ) and bipolar disorder (BD) are the most severe neuropsychiatric disorders affecting 1.2% and 4.4% of Americans, respectively. Certain genes coding for proteins involved in pre-synaptic machinery are thought to play a role in the pathophysiology of the disorder. Deficits in the calcium channel regulator gene NRXN3 have been associated with behaviors of impulsivity and alcohol and drug dependence, which are traits characteristic of BD and SZ. |
| Země: | Kérwá |
| Instituce: | Universidad de Costa Rica |
| Repositorio: | Kérwá |
| Jazyk: | Inglés |
| OAI Identifier: | oai:kerwa.ucr.ac.cr:10669/100136 |
| On-line přístup: | https://hdl.handle.net/10669/100136 https://doi.org/10.1016/j.biopsych.2017.02.1115 |
| Klíčové slovo: | Schizophrenia Bipolar Disorder NRXN3 |