507. Association of NRXN3 deletion with schizophrenia and bipolar disorder

 

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Bibliographic Details
Authors: Shavit, Ayal, Gonzalez, Jessica, Chavez, Maricela, Rodriguez, Marco A., Camarillo, Cynthia, Ramírez, Mercedez Ellis, Zavala, Juan Manuel, Contreras Rojas, Javier, Raventós Vorst, Henriette, Flores, Deborah Lynne, Jerez Magaña, Álvaro Antonio, Ontiveros Sánchez de la Barquera, José Alfonso, Nicolini Sánchez, José Humberto, Escamilla, Michael A., Gonzalez, Suzanne
Format: actas de congreso
Publication Date:2017
Description:Schizophrenia (SZ) and bipolar disorder (BD) are the most severe neuropsychiatric disorders affecting 1.2% and 4.4% of Americans, respectively. Certain genes coding for proteins involved in pre-synaptic machinery are thought to play a role in the pathophysiology of the disorder. Deficits in the calcium channel regulator gene NRXN3 have been associated with behaviors of impulsivity and alcohol and drug dependence, which are traits characteristic of BD and SZ.
Country:Kérwá
Institution:Universidad de Costa Rica
Repositorio:Kérwá
Language:Inglés
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/100136
Online Access:https://hdl.handle.net/10669/100136
https://doi.org/10.1016/j.biopsych.2017.02.1115
Keyword:Schizophrenia
Bipolar Disorder
NRXN3