An alternative in vitro method for testing the potency of the polyvalent antivenom produced in Costa Rica

 

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون: Gutiérrez, José María, Ávila Agüero, Claudio, Cerdas Fallas, Luis, Rojas Umaña, Ermila
التنسيق: artículo original
تاريخ النشر:1988
الوصف:The ability of several batches of polyvalent antivenom to neutralize indirect hemolytic activity of Bothrops asper venom was studied using a sensitive plate test. All samples of antivenom tested effectively neutralized this activity. A highly significant correlation was observed between neutralization of indirect hemolysis and neutralization of lethal activity. This simple and sensitive in vitro test could be used to monitor antibody levels in horses immunized to produce polyvalent antivenom.
البلد:Kérwá
المؤسسة:Universidad de Costa Rica
Repositorio:Kérwá
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/29152
الوصول للمادة أونلاين:http://www.sciencedirect.com/science/article/pii/0041010188900104
https://hdl.handle.net/10669/29152
كلمة مفتاحية:Animals
Antivenins
Costa Rica
Crotalid Venoms
Hemolysis
Drug Effects
Horses
Immunology
In Vitro Techniques
Mice
Neutralization Tests
Snake venom