Synthesis and Evaluation of Aromatic Surfactants as Potential Antibacterial and Cytotoxic Agents

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Autors:	Barrantes Jiménez, Kenia, Fuentes, Mary, Chacón Jiménez, Luz María, Achí Araya, María Rosario, Vázquez Tato, José, Vázquez Tato, María del Pilar, Granados Zúñiga, Jorge, Alvarado, María José, Somarribas Patterson, Luis Felipe, Seijas, Julio A., Soto Tellini, Victor Hugo
Format:	artículo original
Data de publicació:	2019
Descripció:	Two ether and one ester derivatives of the 4-nitro-3-hydroxybenzoic acid were synthesized and characterized. The in vitro antimicrobial and cytotoxic activities of the three novel compounds were also evaluated. The aromatic derivatives showed antibacterial activity against one of the four microorganisms tested and two compounds (C8 and NOBA) had a lower IC50 in HeLa cells.
Pais:	Kérwá
Institution:	Universidad de Costa Rica
Repositorio:	Kérwá
OAI Identifier:	oai:kerwa.ucr.ac.cr:10669/77443
Accés en línia:	http://www.eurekaselect.com/166552/article https://hdl.handle.net/10669/77443
Paraula clau:	Cytotoxic activity Antimicrobial activity Aromatic 4-nitro-3-hidroxybenzoic acid Surfactants Organic chemistry 547 Química orgánica