Synthesis and Evaluation of Aromatic Surfactants as Potential Antibacterial and Cytotoxic Agents

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Autores:	Barrantes Jiménez, Kenia, Fuentes, Mary, Chacón Jiménez, Luz María, Achí Araya, María Rosario, Vázquez Tato, José, Vázquez Tato, María del Pilar, Granados Zúñiga, Jorge, Alvarado, María José, Somarribas Patterson, Luis Felipe, Seijas, Julio A., Soto Tellini, Victor Hugo
Formato:	artículo original
Fecha de Publicación:	2019
Descrição:	Two ether and one ester derivatives of the 4-nitro-3-hydroxybenzoic acid were synthesized and characterized. The in vitro antimicrobial and cytotoxic activities of the three novel compounds were also evaluated. The aromatic derivatives showed antibacterial activity against one of the four microorganisms tested and two compounds (C8 and NOBA) had a lower IC50 in HeLa cells.
País:	Kérwá
Recursos:	Universidad de Costa Rica
Repositorio:	Kérwá
OAI Identifier:	oai:kerwa.ucr.ac.cr:10669/77443
Acesso em linha:	http://www.eurekaselect.com/166552/article https://hdl.handle.net/10669/77443
Palavra-chave:	Cytotoxic activity Antimicrobial activity Aromatic 4-nitro-3-hidroxybenzoic acid Surfactants Organic chemistry 547 Química orgánica