A New Method for the Preparation of 1-Ethynyl Ethers
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| Авторы: | , |
|---|---|
| Формат: | artículo original |
| Дата публикации: | 1994 |
| Описание: | During our study of the stannylcupration of acetylenic ethers we required [2-13C]-1 for mechanistic studies. Existing methods for the synthesis of acetylenic ethers involve dehydrohalogenation of 2-halo, 1,2-dihalo vinyl ether, or haloacetals using KOH, NaNH2, or n-BuLi. These procedures are incompatible with labile functional groups and, if applied to the preparation of 13C-labeled compounds, would require regiospecific preparation of 1- or 2-13C-labeled halo vinyl ethers, which is cumbersome. We report a new, general and efficient method for the preparation of acetylenic ethers which we have applied to the preparation of 13C-labeled and functionalized acetylenic ethers |
| Страна: | Kérwá |
| Институт: | Universidad de Costa Rica |
| Repositorio: | Kérwá |
| Язык: | Inglés |
| OAI Identifier: | oai:kerwa.ucr.ac.cr:10669/87966 |
| Online-ссылка: | https://pubs.acs.org/doi/10.1021/jo00103a059 https://hdl.handle.net/10669/87966 |
| Ключевое слово: | QUÍMICA ORGÁNICA MÉTODO EXPERIMENTAL HIDRÓGENO QUÍMICA COMPUESTO QUÍMICO |