A Biocomputational Platform for Template-based Protein-protein Docking

 

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Autors: Román-Brenes, Ricardo, Siles-Canales, Francisco, Zamora-Mata, Daniel
Format: artículo original
Estat:Versión publicada
Data de publicació:2020
Descripció:We propose the creation of a Biocomputational Platform for template-based protein-protein docking that aims reduce computational time by clustering data before the rigid body alignment. Using data from the Dockground project, models will be created using multiple clustering methods that will annotated each protein into a class, such that when performing the match search, not all of the databank needs to be inspected but just the class that resembles the most to the studied protein. This will reduce the time that conformation matching requires without incurring in lower precision.
Pais:Portal de Revistas TEC
Institution:Instituto Tecnológico de Costa Rica
Repositorio:Portal de Revistas TEC
Idioma:Inglés
OAI Identifier:oai:ojs.pkp.sfu.ca:article/5084
Accés en línia:https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/5084
Paraula clau:Clustering
protein-protein docking
template-based docking
HPC
Agrupamiento
acoplamiento de proteínas
Acoplamiento basado en plantillas