A Biocomputational Platform for Template-based Protein-protein Docking

 

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφείς: Román-Brenes, Ricardo, Siles-Canales, Francisco, Zamora-Mata, Daniel
Μορφή: artículo original
Κατάσταση:Versión publicada
Ημερομηνία έκδοσης:2020
Περιγραφή:We propose the creation of a Biocomputational Platform for template-based protein-protein docking that aims reduce computational time by clustering data before the rigid body alignment. Using data from the Dockground project, models will be created using multiple clustering methods that will annotated each protein into a class, such that when performing the match search, not all of the databank needs to be inspected but just the class that resembles the most to the studied protein. This will reduce the time that conformation matching requires without incurring in lower precision.
Χώρα:Portal de Revistas TEC
Ίδρυμα:Instituto Tecnológico de Costa Rica
Repositorio:Portal de Revistas TEC
Γλώσσα:Inglés
OAI Identifier:oai:ojs.pkp.sfu.ca:article/5084
Διαθέσιμο Online:https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/5084
Λέξη-Κλειδί :Clustering
protein-protein docking
template-based docking
HPC
Agrupamiento
acoplamiento de proteínas
Acoplamiento basado en plantillas