A Biocomputational Platform for Template-based Protein-protein Docking

 

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Библиографические подробности
Авторы: Román-Brenes, Ricardo, Siles-Canales, Francisco, Zamora-Mata, Daniel
Формат: artículo original
Статус:Versión publicada
Дата публикации:2020
Описание:We propose the creation of a Biocomputational Platform for template-based protein-protein docking that aims reduce computational time by clustering data before the rigid body alignment. Using data from the Dockground project, models will be created using multiple clustering methods that will annotated each protein into a class, such that when performing the match search, not all of the databank needs to be inspected but just the class that resembles the most to the studied protein. This will reduce the time that conformation matching requires without incurring in lower precision.
Страна:Portal de Revistas TEC
Институт:Instituto Tecnológico de Costa Rica
Repositorio:Portal de Revistas TEC
Язык:Inglés
OAI Identifier:oai:ojs.pkp.sfu.ca:article/5084
Online-ссылка:https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/5084
Ключевое слово:Clustering
protein-protein docking
template-based docking
HPC
Agrupamiento
acoplamiento de proteínas
Acoplamiento basado en plantillas