Optimization of a metabolic pathway in Escherichia coli for the production of farnesene through the use of synthetic biology

 

Đã lưu trong:
Chi tiết về thư mục
Nhiều tác giả: Garro-Monge, Giovanni, García-Gómez, David, Valerín-Berrocal, Karla, Jiménez-Quesada, Karol
Định dạng: artículo original
Trạng thái:Versión publicada
Ngày xuất bản:2018
Miêu tả:Interest compounds generation using organic waste as raw material results in an economically and industrially viable option. Through synthetic biology is possible the design of microorganisms capable of using these residues as carbon sources in order to produce biofuels, vaccines, alcohol, oils and other products. Farnesene production and its precursors is possible through the genetic modification of microorganisms like Escherichia coli, introducing metabolic pathways capable of produce the interest compounds. After studying, optimizing and synthesizing the genes that make up the metabolic pathway of mevalonate, which originates farnesene, these were assembled together with several Anderson family promoters to transform E. coli and generate E, E, -farnesene from synthetic form.
Quốc gia:Portal de Revistas TEC
Tổ chức giáo dục:Instituto Tecnológico de Costa Rica
Repositorio:Portal de Revistas TEC
Ngôn ngữ:Español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/3957
Truy cập trực tuyến:https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/3957
Từ khóa:Biología sintética
farneseno
RFC10
ruta de mevalonato
terpenoides
Sinthetic biology
farnesene
mevalonate pathway
terpenes