Genetic Bases of Schizophrenia: “Nurture vs. Nature”

 

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Auteur: Raventós Vorst, Henriette
Format: artículo original
Statut:Versión publicada
Date de publication:2026
Description:The present article reviews the scientific evidence demonstrating the heritability of schizophrenia, its complex mode of inheritance and possible genetic and environmental heterogeneity. Linked chromosomal loci and candidate genes are presented. The objective is to present the most important results in the field of schizophrenia genetics. Although the participation of environmental factors in the etiology of this disorder is widely accepted, they are not discussed in this paper. Finally, the lamarkian model presented by Prof. Bolaños is discussed. The goal is to convince that there is no contradiction between the psychological and biological model at present. The modern view of schizophrenia unifies both models: the disorder is considered as a neurodevelopmental disorder with disease susceptibility causing genes, epigenetic factors and environmental noxa, including psychosocial factors.
Pays:Portal de Revistas UCR
Institution:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Langue:Español
OAI Identifier:oai:portal.revistas.ucr.ac.cr:article/11857
Accès en ligne:https://revistas.ucr.ac.cr/index.php/ap/article/view/11857
Mots-clés:Schizophrenia
complex inheritance
genetic heterogeneity
esquizofrenia
herencia compleja
heterogeneidad genética