Acción vaso-periférica del extracto acuoso de las hojas de Clusia coclensis (Clusiaceae)
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| Nhiều tác giả: | , |
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| Định dạng: | artículo original |
| Trạng thái: | Versión publicada |
| Ngày xuất bản: | 1998 |
| Miêu tả: | Aqueous leaf extraet of Clusia coclensis was applied at a dose of 40 mglkg intravenously to isolated posterior extremities of six normotensive Sprague-Dawley rals and six Spontaneously Hipertensive rats anaesthelÍzed wíth sodium nembutal. The perfusion was done in the abdominal artery using as carrier Krebs bicarbonate ringer at 37°C and keeping constant perfusion pressures of 100 mmHg in normotensive rats and 150 mmHg in hipertensive rats. The venous return was measured in the inferior vena cava. The extract induced a significant reduction of the venous return begining 2 min after application, in both rat types. This may reflect a peripheral vasoconstriction that, in whole organism, would have an hipertensive effec!. Therefore, the mechanism of the alledgedly systemic hipotensive effeet of the aqueous extract of Clusia coclensis leafs resides probably at a central level, probably acting by a reduction of the con" tractibility of the myocardium. |
| Quốc gia: | Portal de Revistas UCR |
| Tổ chức giáo dục: | Universidad de Costa Rica |
| Repositorio: | Portal de Revistas UCR |
| Ngôn ngữ: | Español |
| OAI Identifier: | oai:portal.ucr.ac.cr:article/20113 |
| Truy cập trực tuyến: | https://revistas.ucr.ac.cr/index.php/rbt/article/view/20113 |
| Từ khóa: | clusia coclensis guttiferae cardiovascular effects traditional medicine herbal medicine hypertension ieg perfusion |