Cannabis-Based Therapies for Chronic Orofacial Pain: A Systematic Review and Meta-Analysis
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| Autori: | , , , , , , , , , , |
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| Natura: | artículo original |
| Status: | Versión publicada |
| Data di pubblicazione: | 2026 |
| Descrizione: | To evaluate the effectiveness of cannabis-based therapies in managing chronic pain associated with TMDs, periodontitis, and oral cancer. Chronic orofacial pain, especially in temporomandibular disorders (TMDs), presents a challenge in dental practice. Traditional treatments often have adverse effects and limited efficacy. Cannabis has emerged as a potential alternative due to its analgesic and anti-inflammatory properties. A systematic review and meta-analysis of randomized controlled trials, cohort, and case-control studies was conducted using five databases. Risk of bias was assessed using Cochrane ROB 2.0 and ROBINS-I tools. Six studies were included. Cannabis showed significant pain relief in oral cancer (OR=1.46; 95% CI: 1.24-1.71), while effects in TMDs and periodontitis were inconclusive. Cannabis may benefit oral cancer pain management; further studies are needed for TMDs and periodontitis. |
| Stato: | Portal de Revistas UCR |
| Istituzione: | Universidad de Costa Rica |
| Repositorio: | Portal de Revistas UCR |
| Lingua: | Inglés |
| OAI Identifier: | oai:portal.revistas.ucr.ac.cr:article/3386 |
| Accesso online: | https://revistas.ucr.ac.cr/index.php/rOdontos/article/view/3386 |
| Keyword: | Cannabis; Cannabinoids; Chronic pain; Orofacial pain; Temporomandibular joint disorders; Periodontitis; Oral cancer; Analgesics; Dentistry; Systematic review; Meta-analysis. Cannabis; Cannabinoides; Dolor crónico; Dolor orofacial; Trastornos temporo mandibulares; Periodontitis; Cáncer oral; Analgésicos; Odontología; Revisión sistemática; Metaanálisis. |