Brucella Phylogeography across Italy, the Mediterranean, and Europe
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| 著者: | , , |
|---|---|
| フォーマット: | artículo original |
| 状態: | Versión publicada |
| 出版日付: | 2026 |
| その他の書誌記述: | The phylogeographic structure of Brucella melitensis, Brucella abortus, and Brucella suis bv2 reveals distinct evolutionary lineages and geographic patterns. Most Brucella species likely emerged in the Fertile Crescent and moved with the domesticated animals dur- ing the Neolithic expansion of the nomad populations highlighting ancient evolutionary events. Whole-genome sequencing (WGS) and multilocus variable-number tandem-repeat analysis (MLVA) have identified four major lineages of B. melitensis, with geographic segregation. In particular, the West Mediterranean lineage is prevalent in Italy and shows further regional differentiation. Similarly, B. abortus exhibits four main lineages, with Italian strains showing both unique regional diversity and connections to global lineages. B. suis bv2 forms diverse clades across Europe, strongly linked to wild boar populations and suggesting complex evolutionary dynamics. At a smaller scale, clearer geographic patterns emerge, reflecting historical animal trade and links to livestock breed phylogeography, indicating intricate dissemination routes. MLVA and WGS-based approaches are high-resolution tools for tracing outbreaks, understanding local and global transmission, and supporting brucellosis control efforts. This underscores the crucial role of integrated molecular genotyping and epidemiological surveillance in effectively mapping Brucella dIversity and spread. |
| 国: | Portal de Revistas UNA |
| 機関: | Universidad Nacional de Costa Rica |
| Repositorio: | Portal de Revistas UNA |
| 言語: | Inglés |
| OAI Identifier: | oai:www.revistas.una.ac.cr:article/22332 |
| オンライン･アクセス: | https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/22332 |
| キーワード: | Brucella Phylogeography |