Smart and advanced biomaterials for regenerative medicine and tissue engineering

 

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Библиографические подробности
Автор: Mata, Alvaro
Формат: artículo original
Статус:Versión publicada
Дата публикации:2019
Описание:There is great interest to develop new materials with properties that resemble those of biological systems such as hierarchical organization, the capacity to grow or self-heal, and the ability to guide complex biological processes. These kinds of materials would open opportunities to engineer tissues with a much-needed higher level of complexity and overcome major obstacles in regenerative medicine. To this end, supramolecular chemistry offers an exciting opportunity to grow such materials from the bottom-up using molecules and processes found in nature. However, the ability to transform molecular and nano-scale design into functional devices with practical utility at the macroscale remains a challenge.The paper will describe new strategies that integrate supramolecular chemistry with engineering principles to develop practical materials with tuneable and advanced properties such as hierarchical organization, the capacity to grow, tuneable mechanical properties, and specific bioactivity (Inostroza-Brito et al. 2015; Aguilar et al. 2017; Elsharkawy et al. 2018; Hedegaard et al. 2018). These materials are being used towards new regenerative therapies of tissues such as enamel, bone, and blood vessels as well as creating more biologically relevant in vitro models.
Страна:Portal de Revistas UNA
Институт:Universidad Nacional de Costa Rica
Repositorio:Portal de Revistas UNA
Язык:Inglés
OAI Identifier:oai:ojs.www.una.ac.cr:article/13282
Online-ссылка:https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13282