Magnesium homeostasis: physiological and pathological implications.
Gorde:
| Egileak: | , , , |
|---|---|
| Formatua: | artículo original |
| Egoera: | Versión publicada |
| Argitaratze data: | 2018 |
| Deskribapena: | Moderate or severe Mg2+ deficiency produces biochemical abnormalities and clinical manifestations associated with skeletal and cardiac muscles, and renal pathologies. Mg2+ is involved in many homeostatic processes such as energetic metabolism, genetic material duplication and transcription, transport of substances across the cell membrane and enzymatic reactions. Regulation of intracellular and extracellular Mg2+ concentration depends on hormonal factors (insulin and parathormone), intestinal factors (paracellular absorption), renal factors (Henle loop reabsorption); as well as reservation deposits in bones and muscles. Even though a wide variety of food contains Mg diet has a low intake of Mg2+. The hypomagnesaemia prod pathological processes such as cramps, arrhythmias and arterial hypertension. This review pretends to describe the basis of the human physiology of Mg2+ functions, absorption regulation excretion and homeostatic pathways, as well as the clinical importance of low intake of Mg2+ effects, which become more prevalent. |
| Herria: | Portal de Revistas UCR |
| Erakundea: | Universidad de Costa Rica |
| Repositorio: | Portal de Revistas UCR |
| Hizkuntza: | Español |
| OAI Identifier: | oai:archivo.portal.ucr.ac.cr:article/34579 |
| Sarrera elektronikoa: | https://archivo.revistas.ucr.ac.cr/index.php/medica/article/view/34579 |
| Gako-hitza: | magnesium homeostasis hypomagnesaemia striated muscle Magnesio hipomagnesemia músculo estriado |