Immuno-gold replica technique for ultrastructural localization of antigens

 

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Autors: Hernández, Francisco, Rivera, Patricia, Hosaka, Yasuhiro
Format: artículo original
Estat:Versión publicada
Data de publicació:1994
Descripció:We developed a simple method for immunolabelling viral glycoproteins on surface of infected ceil monolayers. Cells 9 hours post-infected with Sendai virus were fixed and treated with polyclonal antibody anti HN glycoprotein (Rabbit IgG), labelled with goat immunoglobulin anti rabbit IgG conjugated with colloidal gold particles. Then, the cells were shadowed with platinum-carbon, covered with nitrocellulose glue, and digested with domestic bleach, washed, and replica fragments were caught with uncovered grid.
Pais:Portal de Revistas UCR
Institution:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Idioma:Inglés
OAI Identifier:oai:archivo.portal.ucr.ac.cr:article/28717
Accés en línia:https://archivo.revistas.ucr.ac.cr/index.php/rbt/article/view/28717
Paraula clau:Sendai virus
immunolabelling
immunoelectronmicroscopy
replica
ultrastructure