In vitro culture of epithelial autografts for treating skin ailments

 

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Auteurs: Calvo-Castro, Laura A., Guerrero-Barrantes, Maritza, Centeno-Cerdas, Carolina, Chaves-Rodríguez, María Inés, Chaves-Solano, Nefertiti, Rojas-Chaves, Miguel
Format: artículo original
Statut:Versión publicada
Date de publication:2015
Description:Worldwide, novel therapeutic strategies have allowed an improvement on the attention and recovery of several skin ailments. However, to date in Costa Rica, there is no treatment, as a current routine protocol, to allow more effective and permanent re-epithelization of patients with chronic or large wounds on the skin. Given the existence of a national program for the production and transplant of skin cells, many patients with skin affections could be treated in the country, with less traumatic and more effective rehabilitation, and with lesser hospital stays. One option to solve this problem, is the in vitro culture of skin cells (fibroblasts and keratinocytes) for the production of autologous dermo-epithelial equivalents for grafting, a procedure currently available at the Tissue Engineering Laboratory (LAINTEC) of the Biotechnology Research Center at the Costa Rica Institute of Technology (ITCR). 
Pays:RepositorioTEC
Institution:Instituto Tecnológico de Costa Rica
Repositorio:RepositorioTEC
Langue:Español
OAI Identifier:oai:repositoriotec.tec.ac.cr:2238/5928
Accès en ligne:https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/2218
https://hdl.handle.net/2238/5928
Access Level:acceso abierto
Mots-clés:Cell culture; tissue culture; tissue engineering; autograft; fibroblast; keratinocyte; skin.
Cultivo celular; cultivo de tejidos; ingeniería de tejidos; autoinjerto; fibroblastos; queratinocitos; piel.