Rotavirus Genotypes in Costa Rica, Nicaragua, Honduras and the Dominican Republic

 

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Autoři: Bourdett-Stanziola, Lurys, Ortega-Barria, Eduardo, Espinoza, Felix, Bucardo, Filemon, Jiménez, Carlos, Ferrera, Annabelle
Médium: artículo
Datum vydání:2010
Popis:In this study, 574 stool samples from children with gastroen- teritis were obtained from different hospitals in Costa Rica, Honduras, Nicaragua and the Dominican Republic during 2005–2006. Diarrhea stool samples were analyzed for rotavi- rus by ELISA and typed by the RT-PCR-based method. Un- usual strains were detected: G1P6, G2P8, G3P6, G9P4 and mixed infections. Recent studies have indicated that unusu- al human rotavirus strains are emerging as global strains, which has important implications for effective vaccine de- velopment. In this context, the next generation of rotavirus vaccines will need to provide adequate protection against diseases caused not only by mixed infections, but also by unusual G/P combinations.
Země:Repositorio UNA
Instituce:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Jazyk:Inglés
OAI Identifier:oai:null:11056/23297
On-line přístup:http://hdl.handle.net/11056/23297
Klíčové slovo:DIARREA
GENOTIPOS
GENOTYPES
VP7
VP4
VIRUS
DI