Evaluación química y biológica del efecto de extractos de plantas contra Plasmodium berghei

 

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Autores: Castro, Oscar, Barrios, Mariano, Chinchilla, Misael, Guerrero, OIga
Formato: artículo
Data de Publicação:1996
Descrição:Extracts from thirteen species of plants were evaluated by "in vivo" antimalarial test against Plasmodium berghei effects. Significant activities were observed in the ethyl acetate and aqueous extracts, elaborated of Cedrela tonduzii leaves, Trichilia havanensis and Trichilia americana bades, Neurolaena lobata and Gliricidia sepium leaves and Duranta repens fruits. Compounds identified include flavonoids, coumarins, mellilotic acid and iridoids which so­rne kind of biodinamic activity has previously been reported. The flavone quercetin 1 purified from C. tonduzii gave strong antimalarial activity, however, its respective glicosides (quercetin 3-glucoside 2 y robinine 7) showed little sig­nificant activity.
País:Repositorio UNA
Recursos:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Idioma:Inglés
OAI Identifier:oai:null:11056/23518
Acesso em linha:http://hdl.handle.net/11056/23518
Palavra-chave:PLASMODIUM BERGHEI
FLAVONES
CATECHINS
COUMARIN
MELLILOTIC ACID
IRIDOIDS
MALARIA
ENFERMEDADES INFECCIOSAS