Intracellular adaptation of Brucella abortus

 

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Autoři: Lamontagne, Julie, Forest, Anik, Marazzo, Elena, François, Denis, Butler, Heather, Michaud, Jean-François, Boucher, Lyne, Pedro, Ida, Villeneuve, Annie, Sitnikov, Dmitri, Trudel, Sylvie, Nassif, Najib, Boudjelt, Djamila, Tomaki, Fadi, Chaves-Olarte, Esteban, Guzman-Verri, Caterina, Brunet, Sylvain, Côté-Martin, Alexandra, Hunter, Joanna, Moreno, Edgardo, Paramithiotis, Eustache
Médium: artículo
Datum vydání:2009
Popis:Macrophages were infected with virulent B. abortus strain 2308 or attenuated strain 19. Intracellular bacteria were recovered at different times after infection and their proteomes compared. The virulent strain initially reduced most biosynthesis and altered its respiration, adaptations reversed later in infection. The attenuated strain was unable to match the magnitude of the virulent strain’s adjustments. The results provide insight into mechanisms utilized by Brucella to establish intracellular infections
Země:Repositorio UNA
Instituce:Universidad Nacional de Costa Rica
Repositorio:Repositorio UNA
Jazyk:Inglés
OAI Identifier:oai:https://repositorio.una.ac.cr:11056/18373
On-line přístup:http://hdl.handle.net/11056/18373
Access Level:acceso abierto
Klíčové slovo:BRUCELOSIS
BRUCELLA
BRUCELLA ABORTUS
VIRULENCE
ENFERMEDADES INFECCIOSAS
INTRACELLULAR INFECTION
BACTERIAS

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