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1

Kérwá

artículo

Low pH formulation of whole IgG antivenom: Impact on quality, safety, neutralizing potency and viral inactivation

by Solano, Silvia, Segura Ruiz, Álvaro, León Montero, Guillermo, Gutiérrez, José María, Burnouf, Thierry

Published 2012

Institution: Universidad de Costa Rica

Repositorio: Kérwá

2

Kérwá

artículo

Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa

by Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, León Montero, Guillermo, Harrison, Robert A., Durfa, Nandul, Nasidi, Abdulsalami, Calvete Chornet, Juan José, Theakston, R. David G., Warrell, David A., Gutiérrez, José María

Published 2010

Institution: Universidad de Costa Rica

Repositorio: Kérwá

3

Kérwá

artículo

Effect of Preservatives on IgG Aggregation, Complement-activating Effect and Hypotensive Activity of Horse Polyvalent Antivenom Used in Snakebite Envenomation

by García González, Mildred, Monge Monge, María, León Montero, Guillermo, Lizano González, Sergio, Segura, Eduardo, Solano Trejos, María Gabriela, Rojas Céspedes, Gustavo, Gutiérrez, José María

Published 2002

Institution: Universidad de Costa Rica

Repositorio: Kérwá

4

Kérwá

artículo

Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without β-propiolactone, in the treatment of Bothrops asper bites in Colo...

by Otero Patiño, Rafael, León Montero, Guillermo, Gutiérrez, José María, Rojas Céspedes, Gustavo, Toro, María Fabiola, Barona, Jacqueline, Rodríguez, Verónica, Díaz, Abel, Núñez Rangel, Vitelbina, Quintana, Juan Carlos, Ayala, Shirley, Mosquera, Diana Carolina, Conrado, Lesdy L., Fernández, Diego, Arroyo, Yobana, Piniagua, Carlos A., López, Mercedes, Ospina, Carlos E., Alzate, Claudia, Fernández, Jorge, Meza, Jazmín J., Silva, Juan F., Ramírez, Patricia, Fabra, Patricia E., Ramírez, Eugenio, Córdoba, Elkin, Arrieta, Ana Berta, Warrell, David A., Theakston, R. David G.

Published 2006

Institution: Universidad de Costa Rica

Repositorio: Kérwá

5

Kérwá

artículo

Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming

by Gutiérrez, José María, Lomonte, Bruno, León Montero, Guillermo, Alape Girón, Alberto, Flores Díaz, Marietta, Sanz, Libia, Angulo Ugalde, Yamileth, Calvete Chornet, Juan José

Published 2009

Institution: Universidad de Costa Rica

Repositorio: Kérwá

6

Kérwá

artículo

Stability of equine IgG antivenoms obtained by caprylic acid precipitation: Towards a liquid formulation stable at tropical room temperature

by Segura Ruiz, Álvaro, Vargas Arroyo, Mariángela, Herrera Vega, María, González, Esteban, Solano Trejos, María Gabriela, Gutiérrez, José María, León Montero, Guillermo

Published 2009

Institution: Universidad de Costa Rica

Repositorio: Kérwá

7

Kérwá

artículo

Modulation of the Susceptibility of Human Erythrocytes to Snake Venom Myotoxic Phospholipases A2: Role of Negatively Charged Phospholipids as Potential Membrane Binding Sites

by Díaz Oreiro, Cecilia, León Montero, Guillermo, Rucavado Romero, Alexandra, Rojas Campos, Norman, Schroit, Alan J., Gutiérrez, José María

Published 2001

Institution: Universidad de Costa Rica

Repositorio: Kérwá

8

Kérwá

artículo

Preclinical evaluation of caprylic-acid fractionated IgG antivenom for the treatment of taipan (Oxyuranus scutellatus) envneoming in Papua New Guinea

by Vargas Arroyo, Mariángela, Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Estrada Umaña, Ricardo, Cerdas Solís, Maykel, Paiva, Owen K., Matainaho, Teatulohi, Jensen, Simon D., Winkel, Kenneth D., León Montero, Guillermo, Gutiérrez, José María, Williams, David J.

Published 2011

Institution: Universidad de Costa Rica

Repositorio: Kérwá

9

Kérwá

artículo

Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom

by Solano Trejos, María Gabriela, Segura Ruiz, Álvaro, Herrera Vega, María, Gómez Argüello, Aarón, Villalta Arrieta, Mauren, Gutiérrez, José María, León Montero, Guillermo

Published 2010

Institution: Universidad de Costa Rica

Repositorio: Kérwá

10

Kérwá

artículo

Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa

by Calvete Chornet, Juan José, Cid, Pedro, Sanz, Libia, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, León Montero, Guillermo, Harrison, Robert A., Durfa, Nandul, Nasidi, Abdulsalami, Theakston, R. David G., Warrell, David A., Gutiérrez, José María

Published 2010

Institution: Universidad de Costa Rica

Repositorio: Kérwá

11

Kérwá

artículo

Role of the animal model on the pharmacokinetics of equine-derived antivenoms

by Rojas Araya, Alicia, Vargas Arroyo, Mariángela, Ramírez Arguedas, Nils Antonio, Estrada Umaña, Ricardo, Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Gómez Argüello, Aarón, Gutiérrez, José María, León Montero, Guillermo

Published 2013

Institution: Universidad de Costa Rica

Repositorio: Kérwá

12

Kérwá

artículo

Snake venomics and antivenomics of Protobothrops mucrosquamatus and Viridovipera stejnegeri from Taiwan: Keys to understand the variable immune response in horses

by Villalta Arrieta, Mauren, Pla Ferrer, Davinia, Yang, Su Lin, Sanz, Libia, Segura Ruiz, Álvaro, Vargas Arroyo, Mariángela, Chen, Pei Yu, Herrera Vega, María, Estrada Umaña, Ricardo, Cheng, Ya Fen, Lee, Cheng Dow, Cerdas Solís, Maykel, Chiang, Jen Ron, Angulo Ugalde, Yamileth, León Montero, Guillermo, Calvete Chornet, Juan José, Gutiérrez, José María

Published 2012

Institution: Universidad de Costa Rica

Repositorio: Kérwá

13

Kérwá

artículo

Venom of Bothrops asper from Mexico and Costa Rica: Intraspecific variation and cross-neutralization by antivenoms

by Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Vargas Arroyo, Mariángela, Uscanga Reynell, Alfredo, Ponce de León Rosales, Samuel, Jiménez Corona, María Eugenia, Reta Mares, José Francisco, Gutiérrez, José María, León Montero, Guillermo

Published 2012

Institution: Universidad de Costa Rica

Repositorio: Kérwá

14

Kérwá

artículo

Trends in Snakebite Envenomation Therapy: Scientific, Technological and Public Health Considerations

by Gutiérrez, José María, Lomonte, Bruno, León Montero, Guillermo, Rucavado Romero, Alexandra, Chaves Mora, Fernando, Angulo Ugalde, Yamileth

Published 2007

Institution: Universidad de Costa Rica

Repositorio: Kérwá

15

Kérwá

artículo

Snake Venomics of African Spitting Cobras: Toxin Composition and Assessment of Congeneric Cross-Reactivity of the Pan-African EchiTAb-Plus-ICP Antivenom by Antivenomics and Neutral...

by Petras, Daniel, Sanz, Libia, Segura Ruiz, Álvaro, Herrera Vega, María, Villalta Arrieta, Mauren, Solano Centeno, Daniela, Vargas Arroyo, Mariángela, León Montero, Guillermo, Warrell, David A., Theakston, R. David G., Harrison, Robert A., Durfa, Nandul, Nasidi, Abdulsalami, Gutiérrez, José María, Calvete Chornet, Juan José

Published 2011

Institution: Universidad de Costa Rica

Repositorio: Kérwá

16

Kérwá

artículo

Antivenomic Characterization of Two Antivenoms Against the Venom of the Taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia

by Herrera Vega, María, Paiva, Owen K., Pagotto, Ana Helena, Segura Ruiz, Álvaro, Serrano, Solange M. T., Vargas Arroyo, Mariángela, Villalta Arrieta, Mauren, Jensen, Simon D., León Montero, Guillermo, Williams, David J., Gutiérrez, José María

Published 2014

Institution: Universidad de Costa Rica

Repositorio: Kérwá

17

Kérwá

artículo

Immunoglobulin G and F(ab')2 polyvalent antivenoms do not differ in their ability to neutralize hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom

by León Montero, Guillermo, Rojas Céspedes, Gustavo, Lomonte, Bruno, Gutiérrez, José María

Published 1997

Institution: Universidad de Costa Rica

Repositorio: Kérwá

18

Kérwá

artículo

Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches

by Gutiérrez, José María, Sanz, Libia, Flores Díaz, Marietta, Figueroa, Lucía, Madrigal Villalobos, Marvin, Herrera Vega, María, Villalta Arrieta, Mauren, León Montero, Guillermo, Estrada Umaña, Ricardo, Borges, Adolfo, Alape Girón, Alberto, Calvete Chornet, Juan José

Published 2010

Institution: Universidad de Costa Rica

Repositorio: Kérwá

19

Kérwá

artículo

Freeze-dried snake antivenoms formulated with sorbitol, sucrose or mannitol: Comparison of their stability in an accelerated test

by Herrera Vega, María, Tattini Jr., Virgilio, Pitombo, Ronaldo N. M., Gutiérrez, José María, Borgognoni, Camila, Vega Baudrit, José Roberto, Solera, Federico, Cerdas Solís, Maykel, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Vargas Arroyo, Mariángela, León Montero, Guillermo

Published 2014

Institution: Universidad de Costa Rica

Repositorio: Kérwá

20

Kérwá

artículo

Purification of equine whole IgG snake antivenom by using an aqueous two phase system as a primary purification step

by Vargas Arroyo, Mariángela, Segura Ruiz, Álvaro, Villalta Arrieta, Mauren, Herrera Vega, María, Gutiérrez, José María, León Montero, Guillermo

Published 2015

Institution: Universidad de Costa Rica

Repositorio: Kérwá

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