A facile method for the preparation of bishomopropargylic alcohols from acyl chlorides
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| Auteurs: | , |
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| Format: | artículo original |
| Date de publication: | 2014 |
| Description: | Controlled dilithiation of propargyl bromide with two equivalents of n-butyllithium, in the presence of TMEDA, produces the operational equivalent of the dianion 1,3-dilithiopropyne. The latter reacts efficiently with acid chlorides to produce bishomopropargylic alcohols in a single step route and with high regioselectivity and moderate yields. |
| Pays: | Kérwá |
| Institution: | Universidad de Costa Rica |
| Repositorio: | Kérwá |
| Langue: | Inglés |
| OAI Identifier: | oai:kerwa.ucr.ac.cr:10669/88344 |
| Accès en ligne: | https://www.sciencedirect.com/science/article/pii/S0040403914002007 https://hdl.handle.net/10669/88344 |
| Mots-clés: | QUÍMICA 1,3-Dilithiopropyne Propargyl bromide lithiation Homopropargylation Homopropargyl alcohols Bishomopropargyl alcohols |