In vitro activity of BaH1, the main hemorrhagic toxin of Bothrops asper snake venom on bovine endothelial cells
محفوظ في:
| المؤلفون: | , , |
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| التنسيق: | artículo original |
| تاريخ النشر: | 1995 |
| الوصف: | Incubation of BaH1, the main hemorrhagic toxin purified from the venom of Bothrops asper, with endothelial cells caused the appearance of spaces among the cells. This effect became more noticeable with increasing hemorrhagin concentration and longer incubation time. Later, the cells became rounded and detached from the substrate into the medium. Augmentation of Trypan blue did not stain the detached cells, indicating their viability. Moreover, after washing the floating cells from the toxin they could be recultivated: they again spread on the substrate and proliferated, demonstrating that BaHl is not directly cytotoxic to the endothelial cells |
| البلد: | Kérwá |
| المؤسسة: | Universidad de Costa Rica |
| Repositorio: | Kérwá |
| OAI Identifier: | oai:kerwa.ucr.ac.cr:10669/29242 |
| الوصول للمادة أونلاين: | http://www.sciencedirect.com/science/article/pii/004101019500078Z https://hdl.handle.net/10669/29242 |
| كلمة مفتاحية: | Animals Bothrops Cattle Crotalid Venoms Endopeptidases Endothelium Endothelium, Vascular In Vitro Techniques |