Método para la producción de formulaciones inyectables de productos proteicos hemoderivados y productos obtenidos utilizando dicho método

 

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Autors: Segura Ruiz, Álvaro, Vargas Arroyo, Mariángela, León Montero, Guillermo, Angulo Ugalde, Yamileth, Villalta Arrieta, Mauren, Herrera Vega, María
Format: patente
Data de publicació:2011
Descripció:The invention relates to a method for producing injectable pharmaceutical formulations of blood-derived protein materials, including the steps of fractioning the source material in a polymer/salt aqueous two-phasesystem in the presence of phenol, purifying the top phase of the system by means of precipitation with caprylic acid and purifying the bottom phase by means of thermocoagulation, increasing the purity of the materials in both phases through chromatography, removing viral particles by means of the nanofiltration of both preparations, and formulating, stabilizing, and packaging the resulting materials.
Pais:Kérwá
Institution:Universidad de Costa Rica
Repositorio:Kérwá
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/81684
Accés en línia:https://patentscope.wipo.int/search/es/detail.jsf?docId=MX130554150&_cid=P21-KF5O3Y-93432-1
https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=15&ND=3&adjacent=true&locale=en_EP&FT=D&date=20131129&CC=CO&NR=6801650A2&KC=A2
https://hdl.handle.net/10669/81684