Postprandial blood lipid responses to aerobic exercise and niacin therapy in men with metabolic syndrome
Kaydedildi:
| Yazarlar: | , , , , , |
|---|---|
| Materyal Türü: | póster de congreso |
| Yayın Tarihi: | 2007 |
| Diğer Bilgiler: | Purpose: Our purpose was to compare the combined effects of a single session of aerobic exercise and six weeks of extended-release niacin in men with the metabolic syndrome. Methods: Fifteen men meeting NCEP criteria for the metabolic syndrome (46 ± 2 yrs of age; BMI = 34.0 ± 0.8 kg/m2; waist circumference = 107.9 ±2.1 cm; HOMA score = 4.3 ± 0.5; triglycerides = 286 ± 26 and HDL-C = 40 ± 2 mg/dL; % fat = 35 ± 5; VO2max = 27.7 ± 5.1 mL.min-1.kg-1) underwent each of four conditions: Control - high-fat meal only (1000 kcals, 100 g fat); Exercise - exercise performed one hour prior to a high-fat meal; Niacin - high-fat meal consumed after six weeks of extended-release niacin; Niacin + Exercise - high-fat meal consumed after six weeks of extended-release niacin and a single session of exercise. Blood samples were obtained at baseline and at two-hour intervals for up to eight hours following the high-fat meals. Temporal responses for triglyceride and insulin concentrations were measured and total (AUCT) and incremental (AUCI) areas under the curve were calculated for these two variables. Differences were determined using multiple repeated-measures ANOVAs (p < 0.05 for all significant differences). Results: Body weights remained stable over the experimental period. Exercise lowered the triglyceride AUCT by 12%; yet, the 23% and 27% reduction in triglyceride AUCT with Niacin and Niacin + Exercise were significantly lower than Control and Exercise. Exercise, however, was the only condition that significantly lowered the triglyceride AUCI. Compared to Control, Niacin increased insulin concentrations by 54% two hours after the high-fat meal, but by only 38% when combined with exercise. Conclusions: Aerobic exercise and niacin are both effective interventions for reducing postprandial lipemia in men with metabolic syndrome. Exercise and niacin appear to attenuate postprandial lipemia by similar and potentially different mechanisms. |
| Ülke: | Kérwá |
| Kurum: | Universidad de Costa Rica |
| Repositorio: | Kérwá |
| Dil: | Inglés |
| OAI Identifier: | oai:kerwa.ucr.ac.cr:10669/103302 |
| Online Erişim: | https://hdl.handle.net/10669/103302 https://doi.org/10.1249/01.mss.0000274837.08437.e3 |
| Anahtar Kelime: | metabolic syndrome exercise aerobic niacin triglycerides postprandial period |