Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

 

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون: Lomonte, Bruno, Calvete Chornet, Juan José
التنسيق: artículo original
تاريخ النشر:2017
الوصف:This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and discusses how these may be combined through diverse experimental approaches with the goal of achieving a more comprehensive knowledge on the compositional, toxic, and immunological characteristics of venoms. Some recent developments in this field are summarized, highlighting how strategies have evolved from the mere cataloguing of venom components (proteomics/venomics), to a broader exploration of their immunological (antivenomics) and functional (toxicovenomics) characteristics. Altogether, the combination of these complementary strategies is helping to build a wider, more integrative view of the life-threatening protein cocktails produced by venomous snakes, responsible for thousands of deaths every year.
البلد:Kérwá
المؤسسة:Universidad de Costa Rica
Repositorio:Kérwá
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/74788
الوصول للمادة أونلاين:https://jvat.biomedcentral.com/articles/10.1186/s40409-017-0117-8
https://hdl.handle.net/10669/74788
كلمة مفتاحية:Proteomics
Venomics
Antivenomics
Toxicovenomics
Snake venom
571.95 Toxicología