Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

 

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Autors: Lomonte, Bruno, Calvete Chornet, Juan José
Format: artículo original
Data de publicació:2017
Descripció:This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and discusses how these may be combined through diverse experimental approaches with the goal of achieving a more comprehensive knowledge on the compositional, toxic, and immunological characteristics of venoms. Some recent developments in this field are summarized, highlighting how strategies have evolved from the mere cataloguing of venom components (proteomics/venomics), to a broader exploration of their immunological (antivenomics) and functional (toxicovenomics) characteristics. Altogether, the combination of these complementary strategies is helping to build a wider, more integrative view of the life-threatening protein cocktails produced by venomous snakes, responsible for thousands of deaths every year.
Pais:Kérwá
Institution:Universidad de Costa Rica
Repositorio:Kérwá
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/74788
Accés en línia:https://jvat.biomedcentral.com/articles/10.1186/s40409-017-0117-8
https://hdl.handle.net/10669/74788
Paraula clau:Proteomics
Venomics
Antivenomics
Toxicovenomics
Snake venom
571.95 Toxicología