Disease-associated CAG·CTG triplet repeats expand rapidly in non-dividing mouse cells, but cell cycle arrest is insufficient to drive expansion

Eitemau Tebyg

• Longitudinal increases in somatic mosaicism of the expanded CTG repeat in myotonic dystrophy type 1 are associated with variation in age-at-onset
  gan: Morales Montero, Fernando
  Cyhoeddwyd: (2020)
• Individual-specific levels of CTG•CAG somatic instability are shared across multiple tissues in myotonic dystrophy type 1
  gan: Morales Montero, Fernando
  Cyhoeddwyd: (2023)
• A polymorphism in the MSH3 mismatch repair gene is associated with the levels of somatic instability of the expanded CTG repeat in the blood DNA of myotonic dystrophy type 1 patients
  gan: Morales Montero, Fernando
  Cyhoeddwyd: (2016)
• Myotonic dystrophy type 1 (DM1) clinical subtypes and CTCF site methylation status flanking the CTG expansion are mutant allele length-dependent
  gan: Morales Montero, Fernando
  Cyhoeddwyd: (2021)
• Analysis of mutational dynamics at the DMPK (CTG)n locus identifies saliva as a suitable DNA sample source for genetic analysis in myotonic dystrophy type 1
  gan: Corrales Acuña, Eyleen Vanessa
  Cyhoeddwyd: (2019)