ST8-t008-SCCmec IV methicillin-resistant Staphyloccoccus aureus (MRSA) in retail fresh cheese
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| Авторы: | , , , , |
|---|---|
| Формат: | artículo original |
| Дата публикации: | 2024 |
| Описание: | This study reports the finding of 3 ST8-t008-SCCmec IVa (2B) MRSA strains in fresh cheese purchased within a single market in Costa Rica. In line with the finding of the resistance genes mecA, blaZ, mph(C), and msr(A) in their genomes, these bacteria showed phenotypic resistance to multiple β-lactams and erythromycin. Besides, they carry genes for acquired resistance to aminoglycosides (aph(3′)-III) and fosfomycin (fosD), mutations in genes associated with fluoroquinolone resistance (gyrA-85 and parC-80), and genes for a myriad of virulence factors, including adhesins, hemolysins, and exotoxins. Our strains share multiple genomic features with MRSA from the USA300 lineage, which is a widely distributed and highly virulent strain implicated in community infections. As a result, consuming these or similar products could lead to multidrug (MDR) infections in susceptible individuals. These results highlight safety deficiencies in cheese production practices and emphasize the risk of foodborne transmission of hard-to-treat ST8 MRSA strains. |
| Страна: | Kérwá |
| Институт: | Universidad de Costa Rica |
| Repositorio: | Kérwá |
| Язык: | Inglés |
| OAI Identifier: | oai:kerwa.ucr.ac.cr:10669/100133 |
| Online-ссылка: | https://hdl.handle.net/10669/100133 https://doi.org/10.3168/jdsc.2023-0521 |
| Ключевое слово: | CHEESE GENE BACTERIA MICROBIOLOGY |