Chapter 6: Founder variations in isolated populations

 

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Bibliographic Details
Authors: Chavarría Soley, Gabriela, Contreras Rojas, Javier, Raventós Vorst, Henriette
Format: capítulo de libro
Publication Date:2020
Description:Isolated populations, also called population isolates and genetic isolates, present several characteristic features that make them useful in the study of the genetic basis of both Mendelian and complex disorders. The consensus regarding population isolates is that they have been founded by a small number of individuals, followed by a period of genetic isolation and growth. In modern times characterized by widespread mobility of people around the world, few human populations can be considered genetic isolates. In this chapter we outline the reasons for their usefulness in genetic studies and describe the role they have played and continue to play in gene-mapping efforts. Specific examples of gene identification are provided.
Country:Kérwá
Institution:Universidad de Costa Rica
Repositorio:Kérwá
Language:Inglés
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/89427
Online Access:https://www.sciencedirect.com/science/article/pii/B9780128178195000061?via%3Dihub
https://hdl.handle.net/10669/89427
Keyword:GENETICS
HUMAN GENETICS
GENOME