Proteomic analysis of the mandibular glands from the Chinese crocodile lizard, Shinisaurus crocodilurus – another venomous lizard?

 

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Awduron: Calvete Chornet, Juan José, Lomonte, Bruno, Lorente, Carolina, Pla Ferrer, Davinia, Zollweg, Michael, Mebs, Dietrich
Fformat: artículo original
Dyddiad Cyhoeddi:2023
Disgrifiad:Based on its phylogenetic relationship to monitor lizards (Varanidae), Gila monsters (Heloderma spp.), and the earless monitor Lanthanotus borneesis, the Chinese crocodile lizard, Shinisaurus crocodilurus, has been assigned to the Toxicofera clade, which comprises venomous reptiles. However, no data about composition and biological activities of its oral secretion have been reported. In the present study, a proteomic analysis of the mandibular gland of S. crocodilurus and, for comparison, of the herbivorous Solomon Island skink Corucia zebrata, was performed. Scanning electron microscopy (SEM) of the teeth from S. crocodilurus revealed a sharp ridge on the anterior surface, but no grooves, whereas those of C. zebrata possess a flattened crown with a pointed cusp. Proteomic analysis of their gland extracts provided no evidence of venom-derived peptides or proteins, strongly supporting the non-venomous character of these lizards. Data are available via ProteomeXchange with identifier PXD039424.
Gwlad:Kérwá
Sefydliad:Universidad de Costa Rica
Repositorio:Kérwá
Iaith:Inglés
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/89016
Mynediad Ar-lein:https://www.sciencedirect.com/science/article/pii/S0041010123000363?via%3Dihub
https://hdl.handle.net/10669/89016
Allweddair:REPTILES
DANGEROUS MATERIALS
PROTEINS
CHEMICAL ANALYSIS