Synergism between basic Asp49 and Lys49 phospholipase A2 myotoxins of viperid snake venom in vitro and in vivo

Eitemau Tebyg

• Role of enzymatic activity inmuscle damage and cytotoxicity induced by Bothrops asper Asp49 phospholipase A2 myotoxins: are there additional effector mechanisms involved?
  gan: Mora Obando, Diana
  Cyhoeddwyd: (2014)
• Isolation of two basic phospholipases A2 from Bothrops diporus snake venom: comparative characterization and synergism between Asp49 and Lys49 variants
  gan: Bustillo, Soledad
  Cyhoeddwyd: (2019)
• Tyr→Trp-substituted peptide 115-129 of a Lys49 phospholipase A2 expresses enhanced membrane-damaging activities and reproduces its in vivo myotoxic effect
  gan: Lomonte, Bruno
  Cyhoeddwyd: (1999)
• Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect
  gan: Gonçalves Dias, Renata
  Cyhoeddwyd: (2017)
• Structural and functional characterization of myotoxin I, a Lys49 phospholipase A2 homologue from the venom of the snake Bothrops atrox
  gan: Núñez Rangel, Vitelbina
  Cyhoeddwyd: (2004)