C-phycocyanins: Immune system modulation and its possible application as therapy against cancer

 

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書誌詳細
著者: Alfaro-Alfaro, Álvaro Esteban, Alpízar-Cambronero, Valerie, Duarte-Rodríguez, Ana Iris, Feng-Feng, Joana, Rosales-Leiva, Christopher, Mora-Román, Juan José
フォーマット: artículo original
状態:Versión publicada
出版日付:2020
その他の書誌記述:Cancer is a complex, heterogeneous, and dynamic disease, characterized by uncontrolled mitosis. Historically, it has been treated with surgery, radiotherapy and chemotherapy, and in more recent years through immunotherapy. For this, different proteins have been investigated for the modulation of the immune response. A group of these are C-phycocyanins, biliproteins from bluish-green microalgae such as Spirulina platensis. The anti-inflammatory environment in healthy people is a prophylactic measure to reduce the risk of developing a certain type of cancer. Its intake has shown that behavior, by suppressing the release of pro-inflammatory substances. An immunomodulatory effect has also been appreciated by increasing or decreasing the expression of CD59, as well as by causing the macrophage proliferation and the release of inflammatory substances. The latter is an indication that there is insufficient information to corroborate its use as a prophylactic or therapeutic option against cancer. Therefore, the information about natural substances such as this one is transcendental, because although they are more attractive to treat this disease, there are no fully proven therapeutic effects.
国:Portal de Revistas TEC
機関:Instituto Tecnológico de Costa Rica
Repositorio:Portal de Revistas TEC
言語:Español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/4653
オンライン・アクセス:https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/4653
キーワード:cáncer
inmunoterapia
C-ficocianina
respuesta inmune
cancer
immunotherapy
phycocyanin
immune response