Insects as allies in biotechnology: a sevenyears exploration of neotropical social wasps for novel antibiotic compounds
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| المؤلفون: | , |
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| التنسيق: | artículo original |
| الحالة: | Versión publicada |
| تاريخ النشر: | 2024 |
| الوصف: | Insects are one of the most significant organisms in terrestrial ecosystems, but they are also crucial in human-modified environments such as crops and cities. Insects have been the subject of study for a long time, but with the advent of biotechnology, the focus of these studies is shifting. For instance, social insects are being researched due to the symbiotic relationships they maintain with microorganisms that produce antimicrobial substances. For this reason, the Biotechnology Research Center (CIB) of the Instituto Tecnológico de Costa Rica (ITCR) has conducted two studies to determine the presence of actinobacteria in colonies of social wasps and to test their antibiotic activity. The main objective of this paper was to perform a review of the results obtained from the research projects conducted at the Biotechnology Research Center (CIB). As a result of these studies, a collection of 60 actinobacteria has been established, which also inhibited the growth of strains related to human and insect pathogens. Due to these findings, two research projects are being conducted to analyze the genome of the strains with the highest inhibition, and to characterize the secondary metabolites. The findings have shown that wasps belonging to the Epiponini tribe maintain associations with several genera of actinobacteria that exhibit antibiotic activity, and that these strains possess a variety of genes associated with the production of bioactive compounds. The results demonstrate the great potential of these organisms for the discovery of new natural antimicrobial products. |
| البلد: | Portal de Revistas TEC |
| المؤسسة: | Instituto Tecnológico de Costa Rica |
| Repositorio: | Portal de Revistas TEC |
| اللغة: | Español |
| OAI Identifier: | oai:ojs.pkp.sfu.ca:article/7614 |
| الوصول للمادة أونلاين: | https://revistas.tec.ac.cr/index.php/tec_marcha/article/view/7614 |
| كلمة مفتاحية: | Actinobacteria antibiotics breed cells social wasps workers Actinobacterias antibióticos avispas sociales celdas de cría obreras |