Case Report: Pediatric Multiple Sclerosis

 

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Detalles Bibliográficos
Autores: Chang Segura, José Lee, Acuña Quiros, Miriam, Sainz Mejías, Amaya, Rojas Cascante, Anny
Formato: artículo original
Estado:Versión publicada
Fecha de Publicación:2023
Descripción:Pediatric multiple sclerosis is an autoimmune, demyelinating and neurodegenerative disease of the central nervous system that affects individuals under 18 years old, the pathogenesis involves immune responses and secondary axonal damage. About 3 to 10% of MS cases occur in pediatric patients, most of them older than 15 years and mainly affect women. Pediatric MS is characterized by a relapsing-remitting course at onset. The diagnosis is based on the identification of recurrent demyelinating events in CNS separated in time and/or space. Among the differential diagnoses that must be excluded there are other demyelinating pathologies, autoimmune and systemic conditions, hereditary, infectious and metabolic diseases. Patients with pediatric multiple sclerosis take longer to reach irreversible disability states but they do it at an earlier age than those who have adult-onset multiple sclerosis. Therapies used in children are based on the results of observational studies since there are no randomized controlled trials in this population.
País:Portal de Revistas UCR
Institución:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Lenguaje:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/36572
Acceso en línea:https://revistas.ucr.ac.cr/index.php/clinica/article/view/36572
Palabra clave:Multiple Sclerosis, Pediatric Patient, Oligoclonal, Bands, Immunomodulatory Treatment, Magnetic Resonance Imaging
Esclerosis Múltiple, Paciente Pediátrico, Bandas Oligoclonales, Tratamiento Inmunomodulador, Resonancia Magnética