Immuno-gold replica technique for ultrastructural localization of antigens

 

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Autores: Hernández, Francisco, Rivera, Patricia, Hosaka, Yasuhiro
格式: artículo original
状态:Versión publicada
Fecha de Publicación:1994
实物特征:We developed a simple method for immunolabelling viral glycoproteins on surface of infected ceil monolayers. Cells 9 hours post-infected with Sendai virus were fixed and treated with polyclonal antibody anti HN glycoprotein (Rabbit IgG), labelled with goat immunoglobulin anti rabbit IgG conjugated with colloidal gold particles. Then, the cells were shadowed with platinum-carbon, covered with nitrocellulose glue, and digested with domestic bleach, washed, and replica fragments were caught with uncovered grid.
País:Portal de Revistas UCR
机构:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
语言:Inglés
OAI Identifier:oai:portal.ucr.ac.cr:article/28717
在线阅读:https://revistas.ucr.ac.cr/index.php/rbt/article/view/28717
Palabra clave:Sendai virus
immunolabelling
immunoelectronmicroscopy
replica
ultrastructure